Drinkable Cocktail Interferes with Alzheimer’s and Restores Memories


Amyloid beta plaques accumulated in a mouse hippocampus.
Yale researchers have identified a drinkable cocktail of designer molecules that interferes with a crucial first step of Alzheimer’s and even restores memories in mice, they report Jan. 2 in the journal Cell Reports.

Bill Hathaway | scitechdaily.com

The binding of amyloid beta peptides to prion proteins triggers a cascade of devastating events in the progression of Alzheimer’s — accumulation of plaques, a destructive immune system response, and damage to synapses.

“We wanted to find molecules that might have a therapeutic effect on this network,” said senior author Stephen Strittmatter, the Vincent Coates Professor of Neurology, professor of neuroscience, and director of the Yale Alzheimer Disease Research Center.

read more